Chicago, IL -- (Sports Network) - Miguel Cabrera smacked a two-run home run as the Detroit Tigers stopped the Chicago White Sox, 8-3, in the finale of a three-game set at U.S. Cellular Field.

Cabrera finished 3-for-3 with three runs driven in, while Carlos Guillen went 2-for-2 with three walks, three runs scored and an RBI for the Tigers, who stopped a six-game losing streak.

Zach Miner (6-4) was solid on the hill as he gave up just two runs -- one earned -- on seven hits with three strikeouts in six innings of work for Detroit.

Carlos Quentin hit a solo home run, his AL-leading 30th of the season, while Juan Uribe drove in a run for the White Sox, who have lost three of five and hold a half-game lead over Minnesota for first place in the AL Central. Javier Vazquez (8-10) was tagged for five runs on eight hits with four walks and eight strikeouts in seven innings of work.

Detroit grabbed the lead in the third inning as Guillen hit a ground-rule double and Cabrera later ripped a pitch into the left field bullpen for a 2-0 lead.

The Tigers doubled their lead in the fifth. After Curtis Granderson struck out to start the inning, Placido Polanco doubled to left and then scored as Guillen followed with a triple to right. After Magglio Ordonez grounded out, Cabrera followed with an RBI single.

Chicago got a run back in the bottom of the fifth on back-to-back ground-rule doubles from Nick Swisher and Uribe.

In the sixth, the White Sox made it a two-run contest. Paul Konerko hit a one- out single and moved to second on a wild pitch. After Ken Griffey Jr. popped out, Alexei Ramirez hit a grounder to short that Ramon Santiago fielded, but he threw it away and Konerko crossed the plate to make it a 4-2 game.

Detroit, though, got the run back in the seventh as Granderson led off the frame with a shot into the right field bullpen, his 14th home run of the year.

The White Sox got back to within two in the eighth as Quentin hit a solo home run, but two nice defensive plays from Detroit kept it a two-run game.

After the Quentin home run, Jim Thome walked and Konerko followed with a double to the left field corner. Thome attempted to score on the hit, but Ryan Raburn nailed the cutoff man and Thome was easily thrown out at the plate. After Griffey was hit by a pitch, Fernando Rodney took the hill and Ramirez lined a shot to left that looked as if it was going to drop, but Raburn made a diving catch to preserve the lead.

The Tigers scored three times in the ninth to pad their lead. With men on first and second, Ordonez ripped a triple to the right-center gap that brought home Granderson and Guillen and Matt Joyce later doubled to score Ordonez for an 8-3 lead.

Rodney gave up a leadoff double to Swisher in the ninth, but retired the next three batters to earn his second save of the season.

Game Notes:

Chicago has won nine of the 15 games against Detroit this season...Vazquez is 1-5 in his last eight starts...Chicago hosts Boston for three games starting on Friday...Detroit, which went 3-7 on its season-high 10-game road trip, returns home to face the Athletics for three games beginning on Friday...Attendance was 36,383.