One person was injured and roads have been shut down following a crash on Highway 65 and Famoso Road on Wednesday morning.
According to the California Highway Patrol, two big rigs were involved in a crash with a third vehicle.
The CHP's traffic website reported one big rig rolled over and a second jack knifed.
The CHP says at least one person was injured.
Environmental Health has been called to the scene.
No word on when roads will reopen.