An e. coli infection contributed to the death of famed playboy Hugh Hefner.

He died of cardiac arrest and respiratory failure after contracting septicemia, which is a blood infection, and drug resistant e.coli, the Los Angeles Dept. of Public Health said.

Hefner died at his home, called the Playboy Mansion, on Sept. 27, 2017, where he was with his four adult children and wife, Crystal. He was 91 years old and had suffered from a back condition that limited his ability to move around.

The magazine Playboy, Hefner's creation, was founded in 1953. It was the center of his empire built around sexual freedom.