Orozco, 30, was driving with her two children who were injured in the crash.
The driver of the second car was Angelica Gonzales, of Bakersfield, suffered major injuries in the crash. Gonzales, 28, had a 4-year-old girl in the car; police said she did not have any noticeable injuries.
A postmortem examination will be scheduled at a later time for Orozco, the Coroner's Office said.
Shafter Police are investigating the crash. They said drugs and alcohol do not appear to have been a factor in the collision.